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Semaglutide dosage calculator

Semaglutide vials are typically 2–10 mg and doses are usually written in milligrams. Work out your syringe units, the doses in the vial and the cost per dose.

Vial size

Common doses

Draw to this mark

10

units on a U-100 insulin syringe (0.1 mL)

Concentration
2.5 mg/mL
2500 mcg/mL
Doses per vial
20
0.25 mg each
Cost per dose
add a vial cost

Semaglutide reconstitution chart (5 mg vial)

Water addedConcentration0.25 mg0.5 mg1 mg
1 mL5 mg/mL5 units10 units20 units
2 mL2.5 mg/mL10 units20 units40 units
3 mL1.667 mg/mL15 units30 units60 units

Units are marks on a U-100 insulin syringe (1 mL = 100 units).

Semaglutide calculator FAQ

How much bacteriostatic water for a 5 mg semaglutide vial?
2 mL gives 2.5 mg/mL, so a 0.25 mg dose is 0.1 mL — the 10-unit mark on a U-100 syringe. Many people prefer this because early doses land on clean, easy-to-read marks.
How many doses are in a 5 mg semaglutide vial?
At 0.25 mg per week the vial holds 20 doses, at 0.5 mg it holds 10 and at 1 mg it holds 5.
How do you calculate a peptide dose after reconstitution?
Divide the peptide in the vial (mg) by the bacteriostatic water you added (mL) to get mg/mL. Then divide your dose by that concentration to get the volume to draw, and multiply by 100 for the mark on a U-100 insulin syringe.
Does this calculator give medical advice?
No. It is arithmetic only. It does not suggest, endorse or recommend any compound or dose. Talk to a licensed clinician before using any peptide.

Keep the numbers instead of redoing them

Pepprep saves your Semaglutide vials, tracks how much is left as you log doses and shows cost per dose over time — free, and it syncs across your devices.

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Pepprep is a tracking and arithmetic tool. It does not prescribe, diagnose or recommend any compound or dose. See the medical disclaimer.